Background: Total Intravenous Anaesthesia using various drug combinations to produce adequate sedation and analgesia with rapid recovery for short surgical procedures is known for more than two decades. AIM: To compare the haemodynamic responses intra operatively and time to recovery in patients receiving Propofol­Ketamine and Propofol­Fentanyl in short surgical procedures. Design: Randomised controlled study. Material and Method: The study included 100 patients randomly selected into 2 Groups of 50 each. Group 1: received Propofol 1.5mg/kg and Ketamine 1mg/kg (PK group) Group 2: received Propofol 1.5mg/kg and Fentanyl 1 mcg/kg (PF group). Statistical Analysis: Using Chi­Square Test, Student ttest (paired and unpaired). Results and Coclusion: From the present study we concluded that both Propofol­Ketmine and Propofol­Fentanyl are equally safe and effective in Total Intra Venous Anaesthesia for patients undergoing short surgical procedures. Propofol­Ketamine combination has better haemodynamic stability than Propofol­Fentanyl combination. 

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