Objective: The LMA (Laryngeal Mask Airway) is a method to offer endotracheal intubation while avoiding the dangerous side effects of visualization of cords and forcing them apart. The present study is designed to compare the conditions to facilitate the insertion of LMA with the two most used agents Thiopentone and Propofol after adequate pre-induction doses of midazolam and fentanyl. Materials and Methods: A study conducted on 60 patients of either sex belonging to 18 to 50 years of age and ASA grade 1 who were to undergo elective surgeries. Patients were randomly divided into two groups. Both groups received pre-induction doses of Glycopyrrolate (0.2mg), Midazolam (0.5mg/kg) and Fentanyl (1.5mg/kg), and were induced with either Propofol (3mg/kg) or Thiopentone (6mg/kg) to facilitate insertion of LMA. Result: Conditions facilitating LMA insertion and ease of insertion were significantly greater in Propofol group when compared to Thiopentone group. The difference was statistically significant (p<0.0001). Conclusion: In view of better ease of insertion, lesser time taken for insertion and better recovery profiles associated with Propofol seems to be superior to Thiopentone in LMA insertion.