The objective of this review paper was to summarize the existing evidence for juvenile chronic arthritis (JCA) from an overview-based search of PubMed.Evidence from existing studies provides information on differential diagnosis of JCA based upon immunogenetic, etiopathogenetic, antibody-based and autoimmune mechanisms for JCA. Management studies were on medical, surgical, orthopedic and rehabilitation of JCA. Studies also suggested a multidimensional biopsychosocial model suitable for evaluating medical and psychosocial empirical findingswhich acts as a frame of reference for a multi-professional team approach in the care of rheumatic children and their families.

Keywords: Juvenile chronic arthritis; Juvenile arthritis; Pediatric rheumatology.