Macrodactyly affects the foot less frequently than the hand. Macrodactyly has yet to be identified as a cause. A gain-of-function mutation in the PIK3CA pathway causes this form of overgrowth. The two categories of clinical manifestations are static and progressive clinical symptoms. Anteroposterior (AP) measurements are taken on both feet. Young people should have soft tissue reductions, epiphysiodesis, epiphysectomies, osteotomies, and other treatments. Adults are more likely to use arthrodesis and shortening surgeries.The purpose of surgery is to reduce the size of the foot so that standard shoes can be worn and the cosmetic look can be improved.