68 non- pathological dried adult crania were studied measurement between greater palatine foramen and incisive fossa of both right and left side were measured and compared prevalence of greater palatineformen (GPF) in relation to molar teeth on either side was studied. Direction of GPF was also studied. All the measurement was taken by vernier calipers. The comparative study measurement of GPF with incisive fossa on both sides- mean value of right GPF was 37.4 (SD ± 1.22) and mean value of left was 37.2 (SD ± 1.24) and p<0.5 . the p value was insignificant. The prevalence of GPF in relation to molar teeth on both sides Right side 3 (4.41%) opposite to 2nd molar 20 (29.4%) between 2nd and 3rd molar 36 (52.9%)opposite to 3rd molar 9 (13.2%) Behind 3rd molar. On left side 2 (2.94%) opposite to 2nd molar 11 (16%) between 2nd and 3rdmolars 48 (70.5%) opposite to 3rd molar 7 (10.2%) Behind 3rd molar. The direction of position of GPF was on right side 22 (32.3%) forward position, 12 (17.6%) forward lateral position, 34 (50%) forward and medial position on left side, 21 (30.8%) forward position 10 (14.7%) forward and lateral position, 37 (54.4%) forward and middle position. This anatomical approach to GPF will helpful to Dentists, Maxillo facial surgeons and plastic surgeons moreover Anaesthetists too, because morphometric values of mesodermal derivatives’ are uncertain.