The increasing consumption of heavy metals in modern industries leads to an increase in the environmental burden. Nickel signifies a good example of a metal whose use is widening in modern technologies. As a result of the healthier consumption of nickel-containing products, nickel compounds are released to the environment at all stages of production and utilization. Nickel is a convenient metal, particularly in various alloys, in batteries, and in nickel-plating. Nickel compounds are used specifically as catalysts and pigments. In nickel-producing or nickel-using industries, about 0.2% of the workforce may be exposed to considerable amounts of airborne nickel. In addition, nickel release e.g., into cutting oils, and skin contact with nickel-containing or nickel-plated tools and other items may add to an occupational nickel exposure. Nickel is extremely mobile in soil, particularly in acidic soils. There is minute proof that nickel compounds accumulate in the food chain. Management of nickel is done with the help of a detoxifying method, which is done by using vitamin C, dimercaptosuccinic acid (DMSA), 2,3-Dimercapto-1-propane sulfonic acid (DMPS), Garlic, etc. The detection and determination of nickel levels can be done by qualitative as well as quantitative methods etc., with the help of UV, AAS, Voltammetry method, NAA, etc.

Keywords: Nickel; Nickel toxicity; Heavy metals; Nickel poisoning; Pharmacokinetics; etc.