Dental personnel are constantly exposed to many of specific occupational hazards. These leads to various disorders, specific to the profession, which develop and intensify with years. The present paper discusses selected occupational biohazards as well as baseline precautionarymeasures. When dentist deal with the potential carriers of these biohazard they become infected either directly or indirectly. So it is essential for every practitioner of dentistry to know about biohazards.