This article discusses the benefits of Cranialnerve noninvasive neuromodulation (CNNINM), which is a multitargeted rehabilitation therapy that initiates the recovery of multiple damaged or suppressed brain functions affected by neurological disorders. Various Previous works has shown the feasibility of using the tongue as a route to deliver noninvasive electrical signals to the brain though the cranial nerves with afferent glossal innervation. In addition, the anatomy of cranial nerve nuclei within the brainstem allows for possible interaction of the incoming neurostimulatory signal with other anatomical or functional pathways and the possibility of neuromodulation within these and higher centers of the central nervous system (termed Cranial Nerve NonInvasive Neuromodulation or CNNINM). CNNINM appears promising for treatment of full spectrum of movement didorders, and for both attention and memory dysfunction associated with traumatic brain injury.

Keywords: Neurorehabilitation; Neuroplasticity; Neurostimulation; Cranial Nerve; Brainstem; Tongue.