60 Patients included in the study as per inclusive and exclusive criteria. Subjects were included after the ethical committee approval. Informed consent obtained to conduct the study. Subjects were randomly divided in to three groups Group A, Group B and Group C with 20 subjects in each group. Group A and B assessed for neural and contralateral neural mobility and Group C assessed for hamstrings mobility. Four weeks interventions had given to each groups. Group A had given Hamstrings stretch + neural mobilization, Group B had given Hamstring stretch + contralateral neural mobilization, Group C had given Hamstring stretch. Five subjects dropped out, 2 males from Group A and 3 males from Group B. All the subjects reassessed by active knee extension test. Mean of the readings taken for final analysis. Results were calculated using 0.05 level of significance. When comparing the pre and post intervention hamstring mobility between the Group A, B and C results, it was found that hamstring mobility increased more in Group A as compared to Group B and C. From this we can infer that ipsilateral neural stretch accompanied with hamstrings stretch releases ipsilateral hamstrings restriction more compared to contralateral neural stretch accompanied with hamstrings stretching and isolated hamstrings stretch.