Aim: The aim of present research was to evaluate the efficiency of vacuum-assisted closure (VAC) against surgical debridement in diabetic foot ulcerations (DFUs) in stipulations of healing rate, protection, and patient agreement. Material and Methods: Present prospective randomized casecontrol study was performed in surgery department of tertiary care hospital in Kutch, Gujarat, India. Total 46 patients had participated in the study. The participants of the research were subjects with DM aged 18-75 years, with stage 2 or 3 DFU, divided into Group A (patients cured with VAC) or Group B (patients cured with conventional dressings), having equivalent Patients. Treatment effect was evaluated as time taken for manifestation of granulation tissue. Results: The patient’s age was in the center of 35 and 75 years in Group A with a mean age of 56.47 years and amid 38 and 69 years in Group B with a mean age of 54.36 years. By Week 2, wound discharge departed in 8 cases of Group A against not any in the control group. Granulation tissue emerged in 16 patients by the ending of Week 2 whereas it come out in 8 patients in Group B. Conclusion: VAC comes out to be further successful, secure, and patient suitable contrast to conservative dressings for the treatment of DFUs.

Keywords: Diabetic Foot Ulcerations; Granulation Tissue, Kutch; Wound Discharge.