Introduction: Gallstones are hardened deposits of the digestive fluid bile,that can form within the gallbladder. They vary in size and shape from as small as a grain of sand to as large as a golf ball. Gallstones occur when there is an imbalance in the chemical constituents of bile that result in precipitation of one or more of the components. Methodology: A study was carried out in a tertiary care hospital to know the profile of patients with gall stones. Totally 50 patients were considered for their study and these patients were selected by using non probability purposive random sampling technique. Results: The most common presenting complaint was hypogastric (56%) followed by epigastric (24%) and acute cholecystitis (20%). Conclusion: Gallstones are 4-10 times more frequent in older than younger subjects. Biliary cholesterol saturation increases with age.