Introduction: Nano silver itself is not new. It has been used for various applications in consumer and commercial products over the past century without showing adverse effects on patients. Nano-silver dispersions were used as medical products already in the 19th century. Additionally, the concept of Nano-silver being used as a topical antibacterial dates back to the days of Sushrut in the 6th century where finely powdered Silver was used as a topical antibacterial/antiseptic after surgery. Material and Method: Silver ions and the compounds made like nanosilver exhibit a broad antimicrobial profile against bacteria, fungi and virus and also have low toxicity towards animal cells. Various studies have also demonstrated definitive antibacterial property of nanosilver against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, C. albicans, V. Parahaemolyticus, S. enterica, B. anthracis, B. Cereus, Bacillus subtilis, Salmonella entrica and Pseudomonas aeruginosa. Result: Nano silver particles have ability to alter the expression of matrix metallo-proteinases (proteolytic enzymes that are important in various inflammatory and repair processes), suppress the expression of tumor necrosis factor (TNF-α), interleukin (IL)-12, and IL-1b, and induce apoptosis of inflammatory cells. Therefore, nano silver gel also displays an anti-inflammatory action. Conclusion: In conclusion, Silveron gel due to its nano silver particles and unique formulation has the power to protect, penetrate, and heal in cuts, wounds, burns, diabetic foot ulcer, and surgical dressings. Keywords: Silveron Gel; Antimicrobial; Nano Silver.