Background: Relapse is common and stressful aspect among substance abusers. In the present study  an attempt  was made to study relapse precipitants among opioid, alcohol and multiple substance dependence. Methods: A survey was conducted to identify relapse factors associated with relapse to problematic substance abuse in 50 clients enrolled in treatment programme for substance use disorders. Clients were interviewed by using socio-demographic profile sheet, Relapse Precipitate Inventory (RPI) to explore common relapse precipitants among substance abusers. Results: Study  reported more negative state (6.90±2.08) associated with relapse phenomena followed by positive /euphoric events (6.34±2.98). 88% patients reported consumption of substance when looking others are involved in drinking. Conclusion: Future researchers are encouraged to replicate this study and explore more dynamic factors which contribute to relapsed addiction to prevent many behavioral and psychological problems among substance abusers in future. It is also recommended that regular follow up, family and peer support also essential with ongoing rehabilitation to curb relapse.

Keywords: Relapse; Substance abuse;Precipitate.