Objective: To find out the sensitivity of the common points in history and physical examination in cases ofdegenerative cervical spine disease at King Abdul Aziz University Hospital (KAUH), Jeddah. Design: Retrospective study from January 2005 to December 2010. Results: A total of 120 cases were reviewed. 63 (52.5%) were females and 57 (47.5%) were males. The mean age was 55.2 +/- 12.8 years. The most common degenerative cervical spine changes were found at C 5-6 levels. The sensitivities for pain radiation was 60%, for history of numbness was 65%, for history of motor weakness was 70%, for finding of motor weakness was 70%, and finding abnormal sensation was 82.5% and for finding abnormal reflexes was 20%. Conclusion: The sensitivity of the pointed neurological history and physical examination is variable with no significantly reliable point in the history. Finding out abnormal sensation can be helpful in reaching the diagnosis of degenerative cervical spine disease in presence of neck pain. Further diagnostic test(s) is required to confirm the diagnosis prior to initiating the treatment.