Infections in health care settings and hospital settings around the world are major public problems which is a major health risk that leads to increase in mortality and morbidity. The Hospital acquired infections spreads through contaminated hands of the health care givers like doctors, Nurses, other staffs, relatives and friends of the Patients. The nurse is the member of the healthcare team who participates in prevention and protection of patient from infection. Some of the most basic strategies resulting in positive patient outcomes include the practice and promotion of hand hygiene, consistent use of aseptic technique, cleaning and disinfection practices, use of standard precautions. A quantitative study was used to assess the Knowledge, attitude and practice of nursing faculty on infection control and its prevention in medical college attached hospitals of central Karnataka. 100 staff nurses were selected by simple random sampling technique from selected medical college attached hospital of central Karnataka. Structured Knowledge questionnaire, attitude scale and checklist to assess the practice were used to collect the data from sample. Result revealed that Majority of the samples i.e 76% had average knowledge, 96% had favorable attitude and 75% had average practice on hospital Infection control and prevention. There was no association between knowledge, attitude and practice with selected socio demographic at 0.05 level of significance. There was negative relationship between the level of knowledge and attitude, Positive relationship between the level of attitude and practice at 0.01 level of significance. Study concluded that staff nurses should be educated to improve the knowledge regarding infection control and its prevention in hospital and to be trained effectively to have a good infection control practice in hospital setup to control and prevent hospital acquired infection or nosocomial infection to the patient.

Keywords: HCAI’s (Health Care Associated Infection); Nosocomial Infection; Knowledge; Attitude and Practice; Staff Nurses.