Introduction: Lipomatous tumors are one of the most common neoplasms in humans and are one of the very complex areas of soft tissue tumors. These tumors vary greatly in incidence, clinical presentation, gross, microscopic appearance and also in biological behavior. Aim: The goal of this study was to find out the ten year incidence, histological spectrum and demographic features of lipomatous tumors in a tertiary care centre in Kerala. Materials and Methods: This is a retrospective study conducted in Department of Pathology, Sree Narayana Institute of Medical Sciences, Eranakulam. We collected the information regarding all resected cases of lipomatous tumors in last 10 years (April 2009 to March 2019) from departmental records and also from MRD. Tissues were received in 10% formalin, processed and stained with hematoxylin and eosin staining. Results: It is seen that out of 418 lipomatous tumors reported in our department in last ten years, commonest one being mature lipoma followed by angiolipoma. Most of the tumors were benign with one well differentiated liposarcoma and four cases of high grade liposarcoma. Tumors seen more in males (67%). The common sites affected are head and neck, trunk, extremities, shoulder etc. Malignant tumors were seen mainly in elderly population and occur in deeper soft tissues. Conclusions: Detailed histopathological examination combined with novel diagnostic techniques like molecular studies can be more helpful in reaching correct diagnosis and further studies are recommended in this area.

Keywords: Soft tissue, Lipoma; Sarcoma