Background: Fibroid is the commonest tumor of the reproductive tract and frequently encountered problem in gynecological practice. Aim and objectives: To observe the frequency of uterine leiomyoma in relation to age, parity, clinical manifestations, morphology, secondary changes, endometrial status and associated pelvic pathology. Material & methods: Over a period of two years, 1866 hysterectomy specimen sent for histopathology was studied. Uteri with fibroids were included for the study. Clinical data including age, parity, menstrual pattern, presenting symptoms, surgical treatment history of these patients with fibroid was collected and analyzed. Results: Leiomyoma was diagnosed in 350 patients out of 1866 hysterectomies (19.12%). Greater frequency (83.42%) was found in late reproductive and perimenopausal years ie 4th and 5th decade with a mean age of 40.9 years. Most of the patients were multiparous (98.09%). Menorrhagia (46.17%) was the commonest symptom followed by dysmenorrhoea (22%). Most of the leiomyomas were intramural type (55.09%). Degenerative changes were observed in 39.41% of leiomyomas and leiomyomas variants in 2.6% of cases. Conclusion: Leiomyoma is the most common benign tumor of uterus occurring during reproductive age group. Histopathology remains the gold standard method in diagnosing the leiomyoma variants. Accurate histopathological examination is mandatory to rule out malignancy for optimal management and patient well being.

Keywords: Leiomyoma Variants, Hysterectomy; Histomorphology; Degenerative Changes.