Context: Due to increasing demand for blood components, injudicious utilisation of blood products will definitely have serious implications in resource constrained settings. The staff nurses should be fully aware of all the pitfalls and its associated consequences right from receiving the blood bag from the blood bank, till it is transfused to the patient. Aims: This study aims at analysing the impact of the knowledge scores of the staff nurses in Blood transfusion practices on the Key performance indicators of Blood Component administration. Settings and Design: This study was conducted in Blood bank, Saveetha Medical College Hospital, Thandalam, Chennai, Tamil Nadu. The study population comprised of 220 staff nurses in the period of 2015–2017. Methods and Material: This is an observational study with a cross sectional design and quantitative data analysis. The study is based upon a questionnaire approved by the hospital ethical committee and retrospective data collection of the key performance indicators of blood component administration, from the case sheets of the patients who received blood transfusion. Statistical analysis used: Knowledge scores of the staff nurses were computed using the results of the questionnaire. The percentage of key performance indicators of blood component administration were calculated based on a checklist. Results and Conclusion: The knowledge scores of the staff nurses was found to be insufficient which contributed to low fulfilment of key performance indicators. Multiple steps were taken to improve the knowledge of the staff nurse, in blood transfusion, which eventually lead to a favourable increment in the key performance indicators of Blood component administration.

Keywords: Blood Components; Performance Indicators; Blood Transfusion.