Background: Septicaemia is one of the leading causes of mortality and morbidity in the neonates, especially in the developing countries like India. Objective: To evaluate the usefulness of hematological parameters using hematological scoring system and CRP in the early diagnosis of neonatal sepsis and to study relationship between the hematological variables and bacteriological profile. Methods and Materials: Documenting the data in the Performa, 106 cases were undergone for the measurement of haematological parameters according to haematological scoring system and followed by correlation with culture profile. Results: The HSS score performance was analysed and that INC followed by I: M atio showed highest sensitivity. Platelet count had highest negative predicative value. Culture profile showed 30.6% of positive results. Conclusion: The study of hematological parameters using hematological scoring system with blood culture in the early screening and diagnosis of neonatal sepsis aids in timely treatment, decreasing the neonatal morbidity and mortality.

Keywords: Haemotological parameters; Preterm; Blood culture.