Objective: To describe the patterns of histopathological lesions seen in hysterectomy specimens in different age groups. Methods and Materials: The study is done retrospectively from the data collected from the pathology department at a tertiary care hospital. A total of 285 cases were collected over a period of one year and their histopathological slides and clinical records were evaluated. Results: Out of 280 cases majority belonged to the 41–50 age group and the least number of cases had an age of below 30. In the uterus, among lesions of the myometrium, adenomyosis were the maximum followed closely by leiomyomas. In the cervix, cervicitis grossed the highest number of cases followed by squamous cell carcinoma of the cervix. The ovarian pathologies are diverse and were found to be equally distributed. Conclusion: This study outlines the most common lesions seen in various organs of the female reproductive tract in hysterectomy patients. Keywords: Hysterectomy; Endometrial hyperplasia; Adenomyosis; Leiomyoma; Ovarian cystic lesions; Chronic cervicitis.