Background: Transfusion of blood products is a double-edged sword and should use judiciously. Improvements in donor screening and transmissible transfusion diseases testing procedures have led to a decrease in the hazards and risks. However, the dangers of non-infectious complications have become more apparent. These non-infectious complications called as adverse transfusion reactions (ATRs) can either be acute in nature or follow a delayed course. Materials and Methods: A retrospective review of all transfusion reactions reported to the Blood Bank at the tertiary care center between January 2018 and January 2019 was done and analyzed as per Departmental Standard operating procedures. Results: ATRs during or after blood transfusion reported during the one year were 22 (0.28%) out of 7824 units of blood /blood components transfused. ATRs reported were allergic Reactions 10 (45.45%), febrile non hemolytic transfusion reactions (FNHTR) 9 (40.9%), anaphylactic reactions 2 (9.09%) and Isolated hypotension 1 (4.54%). Conclusion: The majority of ATRs were Allergic reactions followed by FNHTRs.

Keywords: Adverse transfusion reactions, hemovigilance, whole blood, FNHTR, Allergic Reactions.