Background: It’s difficult to lead the life with skin disease as it account for a great deal of misery, suffering, incapacity and economic loss. Ekakushta is a vatakapha pradhana tridoshaja vyadhi and is prime among the Kshudra kushtas and its lakshanas resembles with the Psoriasis. There is a need for more comprehensive, economical and safe method of management for Psoriasis. Hence the present study was conducted to evaluate the efficacy of Navakarshaka Kashaya Ghanasatwa in the management of Ekakushta (Psoriasis). Methods: 40 patients of Ekakushta fulfilling the inclusion criteria were randomly selected and divided into 2 groups, comprising 20 patients in each group. Clinical signs and symptoms were given suitable grading according to their severity along with PASI scoring. After completion of the treatment results were assessed and statistically analyzed to know the significance. Results: In total PAASI 48.53% improvement was seen in Group A compared to Group B with significance of 0.0004. After considering overall therapy with all the parameters 47.07% i.e moderate improvement by Navakarshaka Kashaya Ghanasatwa was observed.

Keywords: Navakarshaka Kashaya; Kushta; Ekakushta; Psoriasis.