Background: The present study aimed to determine (i) the effect of a residential yoga therapy program on the perception of illness and life satisfaction in patients with non-communicable diseases and (ii) the relationship between perception of illness and life satisfaction in the study population.

Methods: The patients were recruited from a yoga therapy center. All the patients were assessed for life satisfaction and perception of illness at the baseline and after one week of yoga therapy. Data obtained at baseline after 7 days was compared with paired t-test. Association between perception of illness and life satisfaction were determined using Pearson correlation.

Results: There was significant negative relations between of life satisfaction and perception of illness, the both perception of illness and life satisfaction improve after 7 days of yoga therapy.

Conclusion: Yoga therapy may be useful in improving life satisfaction and to perception of illness. This will facilitate a positive outcome and the patients tends to get maximum benefit of the therapy.