AbstractAim of the Study: The uterine artery Doppler has potentials for screening for complications of impaired placentation like preeclampsia and adverse fetaloutcomes.The purpose of this study was to determine the role of uterine artery Doppler flow velocimetry at 2nd trimester of pregnancy in the early prediction of complications of impaired placentation and elucidate it’s role in stratifying antenatal care. Methods: This prospective study was carried out in the department of obstetrics and gynaecology and radiodiagnosis in Government Rajaji Hospital, Madurai. This study includes 183 pregnant women from January 2016 to January 2017 whose uterine artery resistive index and presence of notching was noted between 2024 weeks of pregnancy. R.I>0.6 and presence of diastolic notch in the uterine artery was considered abnormal. Results: out of 183 recruited cases 141 were lowrisk and 42 cases were high risk for developing preeclampsia, IUGR, SGA, preterm. Out of 141 low risk cases, 130 had normal doppler and 11 had abnormal doppler. Out of 42 high risk cases 27 had normal Doppler and 15 had abnormal doppler. dmong the patients having abnormal doppler study (including high risk and lowrisk patients) developedpreeclampsia and 8 developed adverse fetal outcome. Conclusion: Doppler velocimetry of uterine artery in 2nd trimester of pregnancy can be used as a screening test for complication of abnormal placentation in high risk patients when compared to low risk patients.