Introduction: Corneal ulcer is one of the most common causes of prolonged ocular morbidity and visual impairment in our country. While cataract remains the major cause of reversible visual loss, diseases of the cornea are emerging as an important cause of visual impairment. Corneal lesions were found to be responsible for 9% of all blindness in our country, in a recent national survey by government of India.1 The reported incidenceofcorneal ulceration in South India is 1130 per million population. Objectives: To know the etiology of corneal ulcers based on laboratory investigations done in our hospital regarding the type of pathogen and to determine the most common predisposing factor for corneal ulceration. Methods: This cross-sectional descriptive study included fifty patients attending Ophthalmology Outpatient Department in NRI medical College and Hospital with corneal ulcers during a period of one year i.e. July 2016 to June 2017. They were examined by slit-lamp and corneal scrapings were performed for cultures and smears by using standard protocols. Results: Corneal ulcers are more common inrural