AbstractPancreatitis is a known adverse effect of the nucleoside reverse transcriptase inhibitor drugs-a major drug of the anti-retroviral therapy (ART) which causes premature termination of proviral DNA chain by inhibiting reverse transcriptase enzyme. Drug induced pancreatitis in HIV patients is presented as a sudden onset of abdominal pain, nausea, vomiting and general worsening of health. PURPOSE-To analyse whether pancreatitis presents differently in HIV-seropositive patients compared to the general population and to figure out the prevalence and Incidence of Drug induced Pancreatitis in HIV patients on ART in the tribal belt of southern Rajasthan (mewar region).