Introduction: Seizures in CVT can be divided into presenting seizures and early seizures. Presenting seizures are those that occurred at or before confirmation of CVT diagnosis. There is paucity of data in literature about presenting seizures in CVT patients. Aim of the study: To study the clinical profile and risk factors involved in presenting seizures in CVT patients. Materials and Methods: The study is an observational study conducted in department of neurology in a tertiary care centre in South India. The period of study is from August 2017 to July 2018. Cerebral venous thrombosis was confirmed by MRI Brain with MR venography. Demographic data, clinical findings, Neuroimaging findings and risk factors for CVT of patients with presenting seizures were captured. Descriptive statistics were used wherever necessary. Results: 14 patients out of 78 had presenting seizures (17.94%). 8 patients were female (57.1%) and 6 patients were male (42.9%). Mean age in the study group was 37.42± 2.69. Headache was present in 11 patients (78.57%). Seizures were focal in 4 patients (28.57%) and generalized in 10 patients. (71.43%). Superior sagittal sinus was involved in 7 patients (50%). Supratentorial lesion was seen in 13 patients (92.85%). Lesion in frontal lobe was seen in 6 patients (42.85%). Conclusion: The presenting seizures were more common in females, more frequent in patients with multiple risk factors, more common with frontal lobe involvement and more common with superior sagittal sinus involvement. Incidence of seizures is high in patients with any supratentorial lesion. 

Keywords: CVT; Presenting Seizures.