Abstract Background: Soft tissue tumors are mesenchymal proliferation, that occur in extraskeletal, non-epithelial tissue of the body, excluding the viscera, covering of brain and lymphoreticular system. Benign tumors are more common than malignant soft tissue tumors. Histopathological examination of soft tissue tumor is gold standard method for initial diagnosis and management of patient accordingly. Aims & Objectives: 1) To study the occurrence of soft tissue tumors in relation to age, sex and anatomical site distribution. 2) To study histopathological spectrum of soft tissue tumors. 3) To study frequency of occurrence of benign and malignant soft tissue tumors. Material and Methods: This retrospective study include total 97 soft tissues biopsy specimens which were received from January 2015 to July 2018. After processing and microscopic examination of tissue sections histopathological diagnosis given and tumors were classified according to WHO classification and result were correlated with clinical details of patient. Result: Peak age of incidence of soft tissue tumors was between 2nd to 5th decades. Male: Female ratio was 1:1. Benign tumors (97.93%) were more common than malignant tumors (2.06%). Most common soft tissue tumor was adipocytic tumors. Conclusion: Proper gross examination of the specimen and adequate sampling of the tumors and histopathological diagnosis of tumor by light microscopic evaluation of H&E stained sections remain the gold standard technique for initial diagnosis and further management of soft tissue tumors and is sufficient for the majority of cases.
Keywards: Soft Tissue Tumor; Histopathology; Benign; Malignant