AbstractIntroduction: Pleural diseases involve the parietal and visceral pleura and may be of either inflammatory or malignant origin. Pleural biopsy is recommended for the evaluation of inflammatory, infectious etiologies and malignant diseases. Inflammation can be caused by various conditions such as pneumonia, collagen vascular disorders, drug reactions. Pleural metastasis from pulmonary and extra pulmonary malignancies are common whereas primary tumors of the pleura constitute a relatively rare group of benign and malignant neoplasms. Aim of the study is to identify the incidence of neoplastic and non neoplastic lesions of pleura with focus on immunohistochemistry (IHC). To study the age and gender distribution of pleural lesions. Methods: Two years retrospective study was done from August 2015 to July 2017 at SVS Medical College and Hospital, Mahabubnagar on 70 pleural biopsies sent to the department of pathology. Results: Out of the seventy cases, fifty were inflammatory lesions and twenty were malignancies. Out of the malignant lesions primary pleural malignancies were three cases and the remaining seventeen cases were metastatic deposits to the pleura.
Keywords: Pleural Malignancies; Immunohistochemistry