A 46 years old ladycame to ED with c/o B/L progressive loss of vision since 6 days associated with intermittent
headache. With Left eye perception of hand movements at 10 inches. With Right eye she can see objects about 5
meters but unable to identify color and face MRI orbit contrast/MRI brain contrast s/o B/L optic neuritis with
subtle T2/flair hyperintense signal is seen in the periaqueductal region, ? artefactual, ? changes of NMO/NMOSD
Hematology report revealed anti MOG antibodies:Positive Visual Evoked Potential(VEP) suggestive ofB/L
demyelinating anterior visual pathway defect ANA and vasculitic panel negative. Ophthalmo opinion revealed B/
Lpapilloedema.Keywords: B/L optic neuritis; B/L papilloedema; Anti mog antibodies; Neuromyelitis Optica (NMO); AQP4 India.