Background: Polyhydramnios carries a high rate of complications during pregnancy and adverse perinatal outcomes. The aim of this investigation was to evaluate the Pregnancy oucome in polyhydramnios. Methods: The prospective study carried out in Mangalore Fetal Medicine Centre, which is specialized centre for obstetric ultrasonography from Jan 2014 to June 2016. Possible confounding factors that could affect the occurrence of polyhydramnios were analyzed. We then investigated the relative risks of these events to adverse perinatal outcome by adjusting the variants. Results: Significantly higher incidences of preeclampsia, placental abruption, placenta accreta, past history of fetal death or preterm delivery, multiple pregnancies, bodyweight gain 20kg during pregnancy and primiparity were noted in patients with polyhydramnios than in patients without this condition. The presence of polyhydramnios significantly increased the rate of preterm delivery,low birth weight or very low birth weight, low oneand fiveminute Apgar scores, fetal death, large for gestational age babies, meconiumstained amniotic fluid, Cesarean section, fetal distress in labor, NICU transfer and neonatal death. Conclusions: Polyhydramnios carried a higher incidence of adverse perinatal outcomes,such as low Apgar scores, fetal death, fetal distress in labor, NICU transfer and neonatal death, despite exclusion of congenital anomalies from the study population. Detailed antepartum fetal wellbeing surveillance, intensive intrapartum monitoring and further attention to postpartum is warranted in patients with this condition.

Keywords: Polyhydramnios; Perinatal Outcome; NICU.