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Journal of Plastic Surgery and Transplantation

Volume  3, Issue 1,  January - June 2021, Pages 19-23

 

Review Article

Alopecia and Covid-19 Pandemic: A Review Article
Sameer Bhati1, Naveen Kumar2
Sameer Bhati1, Naveen Kumar2
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DOI:

Abstract

Various dermatologic diseases came into notice worldwide after the COVID-19 pandemic. The stress and the anxiety associated with the COVID-19 pandemic have been seen as the causal factor behind many psychosocial dermatologic diseases, such as psoriasis, chronic urticaria, and alopecia areata. It has been seen that there is increasing likelihood in the occurrence of alopecia area after the COVID-19 outbreak which is usually observed after months of contracting the illness. Alopecia areata is described as a non scarring type of autoimmune hair loss ,recurrent in nature. As emotional stress burden increases, the incidence of alopecia increases, and after the occurrence of alopecia , psychiatric disorders are often triggered. Given the importance of psychiatric disorders in alopecia, after the COVID-19 pandemic, there are numerous stress factors like travel ban, social distancing, gathering, and conveyance restrictions starting to take place. Henceforth this is clearly suggesting that there is a vicious circle between alopecia and psychiatric disorders. There is a high need to study deeply in order to derive any conclusion establishing the relationship between the Alopecia and COVID-19 pandemic. The transcription of transmembrane protease serine 2 (TMPRSS2) regulated by the AR. This protease is important to cleave SARSCoV-2 spike glycoprotein, this cleavage, also termed “priming,” is essential for the spike protein of virus to bind to human angiotensin-converting enzyme 2 (ACE2), needed for the cellular entry for infection. Targeting the TMPRSS2, whether directly or indirectly through androgen pathway with various therapeutic antiviral agents, clearly showed the strong association between the androgenic alopecia and COVID-19 virus


Corresponding Author : Naveen Kumar