AbstractIntroduction: Historically newborn infants were believed to be decorticate beings without the capacity to feel or be affected by pain like adults. Infants were considered comparable to a semi – anesthetized adult. Many surgical procedures, including circumcision, have been routinely performed on infants younger than three months without anesthesia or analgesia. Our knowledge of pain in neonates has increased dramatically in the past two decades. Supported by an impressive body of neuroanatomical, neurochemical, and biobehavioral evidence, term and preterm infants possess the ability to perceive and respond to pain and remember pain experiences. Kangaroo Mother Care has been shown to prevent infections, promote breastfeeding, regulate the baby’s temperature, breathing, and brain activity, decreases pain and encourages mother and baby bonding. So the investigator performed an experimental study to assess the Effectiveness of Kangaroo Mother Care in reducing pain from intravenous procedures among preterm neonates in selected hospitals, Hyderabad. Methodology: Research design selected for the present study was experimental design.18 Premature Infant Pain Scale was used to collect data. The study was conducted at Niloufer children’s hospital Red hills, during a specified period of 14 days. Simple Random sampling technique was used for the selection of sample. Total sample for the study were 60.8 Results: The study results showed that majority of preterm neonates 26 (86.7%) from control group were having severe pain. Majority of preterm neonates in experimental group 28 (93.3%) were having moderate pain. The mean of control group is 15.87 whereas mean of experimental group is 8.67. The calculated t- value (16.187) is more than the table value (2.0017) at the level of 0.05 probability. Hence it can be stated that kangaroo mother care is effective in reducing the pain.11 Keywords: Preterm Neonates Effectiveness; Kangaroo Mother Care; Pain; Intravenous Procedures.3