AbstractDespite its discovery a 100 year ago, vitamin D has emerged as one of the most controvertial nutrient and prohormone of the 21st century. Its role in calcium metabolism and bone health is undisputed yet has non classical action on glucose metabolism, immune function, bacterial infections etc. During pregnancy Vitamin D deficiency induces maternal and neonatal complications. Objective: The aim of our study was to determine the prevelence of Vitamin D deficiency during pregnancy and its consequential effect and complication in mothers and their newborn. Design: A sample size of 50 preganant mothers attending antenatal clinic with suspicion of vitamin D deficiency was picked up for the evaluation that included detailed history, physical examination and Vitamin D level estimation. The extent and severity of Vitaamin D deficiency were analysed, maternal and neonatal outcome were recorded. Result: Majority of womens (60%) had Vitamin D level < 10ng/dl and 28% have insufficiency and 8% had sufficient levels of Vitamin D. Main symptoms were fatigue, bone and muscle pain etc and complications during pregnancy with Vitamin D deficiency were,PIH, oligohydroamnios and GDM. There was a six fold increase in the incidence of caessarean section and significant perinatal complications that were highlighted like asphysia, low birth weight resulting in NICU admission. Conclusion: High prevelence of Vitamin D deficiency during pregancy is increasingly recorganized lead to maternal and perinatal complication. A concious knowledge about in and its adverse impact on mother and the newborn requirs close scrutiny. Universal screening is highly recommended looking to the very high prevelence of Vitamin D deficiency.
Keyword: Vitamin D; PIH; GDM; IUGR; Maternal and Perinatal Outcome.