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Indian Journal of Forensic Medicine and Pathology

Volume  13, Issue 2, April-June 2020, Pages 297-302
 

Original Article

Morphological Spectrum of Renal Lesions: An Autopsy Study

Sainath K Andola1, Pratima Manohar Pattar2, Umesh SR3, Anuradha G Patil4

1Former Dean & Director, Professor, 4Professor & HOD, Department of Pathology, M.R Medical College, Kalaburagi, Gulbarga, Karnataka 585105, India. 2Tutor, Department of Pathology, ESIC Medical College, Kalaburagi, Gulburga, Karnataka 585106, India. 3Professor & HOD, Department of Forensic Medicine, GIMS, Kalaburagi, Gulburga, Karnataka 585105, India.

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DOI: http://dx.doi.org/10.21088/ijfmp.0974.3383.13220.9

Abstract

 

Context: Renal diseases are responsible for a great deal of morbidity and mortality. The autopsy study throws immense light on pathogenesis of disease, reveals hazardous effects of violence on various organs and lastly often reveals the cause of death.
Aims: To study the histomorphological spectrum of renal lesions in autopsies and an attempt is made to establish the cause of death.
Design: Observational type of study.
Materials and Methods: A prospective study was conducted from July 2016 to June 2018 in the department of pathology. A total of 210 kidneys of adult medico legal autopsies performed during the period were included in our study. The stained microscopic sections were examined by two histopathologists independently.
Statistical Analysis: Descriptive analysis using IBM SPSS Statistics for Windows, Version 22.0.
Results: The age ranged from 4 to 80 years. Majority of the cases were in the age group of 21–30 years with a mean age of 33.40 years and the M:F ratio was 1.8:1. Out of 210 cases, 103 cases (49.1%) showed tubulo-interstitial and vascular lesions, 92 cases (43.81%) showed near
normal histology of kidney and 15 cases (7.1%) showed glomerular lesions.
Conclusions: The tubulo-interstitial lesions were more common than glomerular lesions in medicolegal autopsies. The incidental finding in this study highlights the importance of gross and microscopy examination of each organ in detail from each autopsy irrespective of the cause of death.
Keywords: Autopsy; Histomorphology; Renal lesions.


Corresponding Author : Pratima Manohar Pattar