AbstractIntroduction: Blood transfusion is associated with several risks which particularly includes Transfusion Transmissible Infections (TTI’s) like Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human Immunodefeciency Virus (HIV), Syphilis and Malaria. The aim of the study was to find out the prevalence and changing trends of these infections among blood donors in the study area. Materials and Methods: A retrospective analysis of blood donor’s records was done from January 2011 to December 2018. HIV, HBV and HCV infections were tested using ELISA (Enzyme linked Immunosorbent assay) technique. Syphilis was tested by RPR (Rapid plasma reagin) test. Malaria is reported after screening the stained blood smears. Results: Total 14,545 blood donors were screened, comprising of 10,458 voluntary donors and 4,087 replacement donors. The overall seroprevalence of HBV, HIV, HCV and Syphilis was 0.62%, 0.13%, 0.10% and 0.02% respectively with no Malaria infected donor. Conclusion: Though the prevalence of Transfusion transmissible infections is decreasing, there is a need for adopting strict donor selection criterion and use of sensitive screening tests that can minimize the risk of acquiring these infections.
Keywords: Blood donors; Transfusion transmissible Infections; Prevalence.