Introduction: Acinetobacter species are capable of causing infections such as pneumonia, sepsis in wounds, urinary infections, septicemia, endocarditis and meningitis. Apart from hospital acquired infections there has been a rising trend in community acquired infections with Acinetobacter species. It’s intrinsic resistance and multi - drug resistance is posing a major health challenge. Acinetobacter species are becoming increasingly resistant to commonly used antibiotics such as aminoglycosides, fluoroquinolones, broad spectrum B-lactam antibiotics, cephalosporins and carbapenems.11 The aim of this study was to analyse the frequency of isolation of Acinetobacter species in various clinical specimens coming for culture in Microbiology department and also to assess antibiotic sensitivity pattern of the isolates.

Materials and Methods: This prospective study was conducted between January to April 2018 in the Microbiology department of our centre. 2015 clinical specimens from both sexes and all ages like urine, pus, blood, different body fluids like pleural, ascitic, synovial, sputum and endotracheal tube etc were included in the study

Results: Significant growth of Acinetobacter was observed in 10 (1.37%) cases .Acinetobacter was isolated from 3 Pus samples, 4 ET secretion samples, and one each from Urine, Throat swab and Body Fluid samples. The isolates were sensitive to only Colistin and Tigecycline with intermediate resistance to Ciprofloxacin and Cefepime and
resistant to all the other antibiotics in all clinical specimens.

Conclusion: Treatment of infections caused by Acinetobacter species is becoming increasingly difficult due to emergence of multidrug and pan drug resistant strains of Acinetobacter. The rampant and injudicious use of antibiotics is a major cause of this emerging drug resistance. A stringent hospital antibiotic policy and infection control policy should be implemented

Keywords: Acinetobacter Species; ET Secretions; Pan Drug Resistance.