Introduction: Thyroid associated ophthalmopathy is an autoimmune disorder affecting the orbital and periorbital tissues. Hyperthyroidism is commonly associated with thyroid associated ophthalmopathy, however in 5% to 10% of cases it is euthyroid. Genetic, environmental and endogenous factors play a role in the initiation of the thyroid ophthalmopathy. Materials and Methods: This is a prospective study conducted on total 40 patients according to inclusion criteria. All patients underwent a comprehensive ophthalmological examination and radiological examination. Results: In the present study, 5th decade was the most common age group observed with thyroid orbitopathy in 12 cases (30%). Female preponderance was seen with females twice more common than males. Hyper thryroidism (67.5%) is most common thyroid status observed. Uniocular presentation (75%) with right eye involved more frequently 40% than left eye. Sandy and Grittiness (60%) was the most common symptom, Proptosis (90%) was the most common sign and Lid retraction (85%) was the second most common sign observed. Inferior rectus most commonly involved muscle (62.5%) and least involved muscle was lateral recuts (22.5%). Corneal involvement with tear film abnormalities 10%, optic nerve compression 5% and ptosis 5% were observed less severe in our study. Conclusion: In present study we found that 5th decade 12 (30%) with female preponderance and most of the cases are with proptosis.

Keywords: Graves Ophthalmopathy; TAO; Hyperthyroid; Proptosis; Uniocular.