Purpose: A hospital-based survey was conducted in GCS Medical College, Hospital and Research Centre, Ahmedabad, Gujarat, to study epidemiology of glaucoma. Materials and Methods: Detailed history, ocular examination was done in all patients diagnosed with glaucoma. Intra-ocular pressure was measured by Perkins applanation tonometer. Visual acuity was checked using Snellen’s Chart. After dilating the pupil, the fundus was examined, glaucomatous changes in optic disc were noted diagrammatically. Visual field changes were noted from Humphrey perimetry. Gonioscopy was done by 4 mirror gonio lens to determine type of glaucoma. OCT was done for RNFL. Results: Total 1521 patients attending eye OPD of GCSMCH & RC were diagnosed and treated for glaucoma during the period of three years from May 2015 to April 2018 out of which only 161 patients were consistent throughout the study. Rest 1360 patients were lost to follow up. The maximum percentage of patients were between 45 and 60 years of age. Mean base line intra-ocular pressure was 22 mm Hg (SD = ± 0.20). Average cup-disc ratio was 0.6 (SD = ± 0.20). 111 patients (68.94%) were phakic and 50 patients (31.06%) were pseudophakic. POAG patients were 67 (41.61%), PACG patients were 52 (32.29%), PAC and PACS patients contributed to 22 (13.66%) and 20 (12.42%) respectively. 161 glaucoma patients who were primarily treated included 118 (73.29%) patients with medical treatment, 21 (13.04%) patients treated with laser and 14 (8.69%) patients managed surgically by trabeculectomy with mitomycin and 8 (4.96%) patients by cataract extraction following which the angles opened. During the course of our study, 106 number of patients required change of treatment out of which 75 (70.75%) patients were changed with medical line of treatment, 20 (18.87%) patients were changed to laser form of treatment and 11 patients (10.37%) were operated with trabeculectomy with mitomycin. Conclusion: Initiatives to increase public awareness and comprehensive eye examination by ophthalmologists are the key to reduce or eliminate undiagnosed glaucoma and also increase the compliance of the patients. The high non-compliance rate and high prevalance rate of change of treatment is also suggestive of requirement of close follow up and timely intervention to prevent blindness and morbidity related to glaucoma disease. The overall drop out rate was 89.41%. Also further study needs to be done for the reasons of high glaucoma drop out.

Keywords: Glaucoma; Intra-ocular pressure; Gonioscopy; Phakic; Pseudophakic.