Background: Mental health and physical health are essentially intertwined. People living with severe psychiatric disorders are at significant risk of suffering from many physical disorders. The prevalence of depression and anxiety in patients with cardiac disease is little understood. Aims and Objectives: The objective of this study was to assess depression and anxiety in cardiac patients and to determine relationship between them. Materials and Methods: The study sample comprised of 200 outpatients following up in the cardiology Outpatient Department (OPD) of the Mamata General Hospital, a tertiary care hospital in Khammam, Telangana, India over a period of 1 year from March 2019 to March 2020. The samples were drawn using convenience sampling method. Mini International Neuropsychiatric Interview (MINI), Hamilton Anxiety Rating Scale (HAM-A) and Hamilton Depression Rating Scale (HAM-D) were the scales administered. Results: Anxiety and depression were present in 51% and 30% of
the sample respectively. The mean scores of depression and anxiety were significantly high in females than males significantly. Correlation between depression and anxiety showed that depression and anxiety were positively correlated (r=0.738, P=<0.001). Conclusions: Depression and anxiety are associated with cardiac disorders. There is
a need to keep in mind anxiety and depression as comorbidities in cardiac patients for adequate intervention that can be incorporated in management plan.