Background: Coronary artery disease alone accounts for 40% of deaths in diabetics during the 4th decade of life and this amount to 50-70% of deaths above the age of 65 years. Diabetes has become predominantly a disease of the cardiovascular system and hence cardio-dialectology is fast emergingas subspecialty throughout the world to tackle the menace of cardiac related mortality and morbidity in diabetes particularly in NIDDM.

Objective: To determine an giographic profile among diabetics and non diabetics with acutecoronarysyndrome. Methodology: A case control study among 50 diabetics and 50 non diabetic patients with acute coronary syndrome admitted in ICCU, attached to Tertiary care Medical College, Bangalore was carried out for a period of Two Years. Group 1 (Diabetic): Previously known diabetic or first time detected diabetic by American Diabetes Association (ADA) criteria presenting with acute coronarysyndrome. Group 2 (Non-Diabetic): Cases presenting with acute coronary syndrome who are non-diabetic or not fulfilling ADAcriteria.

Results: In the study 50 diabetics and Non diabetics diagnosed with Acute coronary syndrome were included and compared. Among diabetics, 16% were diagnosed to have Unstable Angina, 32% as NSTEMI and 52% as STEMI. Among Non diabetics, 20% were diagnosed to have Unstable Angina, 24% as NSTEMI and 56% as STEMI. Among diabetics, 12% received Medical treatment, 38% underwent PTCA and 50% underwent CABG. Among Non diabetics, 22% received Medical treatment, 62% underwent PTCA and 16% underwent CABG. There was significant difference in Treatment between two groups.

Conclusion: The severity of stenos is and total occlusion of vessels were more commonly seen in diabeticpatients. The incidence of triple vessel or Multivessel disease was significantly high. Majority of the diabetic patients with ACS require CABG as the main mode of treatment.