The ameloblastoma is most common benign odontogenic tumour of ectodermal origin. It represents 1% of all tumours of the jaw. The most common site of occurrence is mandible (75%) involving premolars, molars and angle region. They can also involve maxilla (25%). Ameloblastoma usually occurs in the 4th and 5th decades of life having no sex predilection. It often presents as a slow growing, painless swelling and causing expansion of the cortical bone. It has tendency for local aggressiveness. Ameloblastoma is treated by curettage, enucleation, cryosurgery, marginal, segmental and composite resections depending on the type and nature of ameloblastoma. Recurrence is frequent after inappropriate surgery. Accurate preoperative delineation of the boundaries of the tumour is essential for achieving a complete resection. This case report emphasizes on gigantiform ameloblastoma which resembles ameloblastoma but having more aggressive spread and high morbidity and mortality rate.