Myasthenia gravis patients represent a significant management problem for the anesthesiologist, as the anesthetic considerations in these patients include a marked sensitivity to the non-depolarizing skeletal muscle relaxants and an increase in the risk of prolonged postoperative mechanical ventilation. Regional anesthesia, including USG guided nerve blocks are an excellent option, wherever feasible. In situations where regional techniques are contraindicated or fail to provide surgical anesthesia, general anesthesia without muscle relaxants can be a handy option.