Context: The study was conducted to establish a co-relation between Sonoclot parameters and blood and blood product during on-pump cardiac surgeries.

Aims: To estimate the amount of blood and blood
product transfusion and post-operative drain are affected by Sonoclot-guided transfusion therapy.

Settings
and Design: Randomised controlled Study

Methods and Material: Total of 120 patients were randomly assigned
by computer generation to either Sonoclot guided therapy or routine hospital therapy. Patients of either sex undergoing on-pump complex cardiac surgical procedures. Patients having pre-existing hepatic disorders, a renal disease requiring dialysis, and those who received anticoagulant or antiplatelet drugs within one week of surgery were excluded.

Statistical analysis used: Data were analyzed using descriptive statistics to get the frequency distribution & the Independent Sample T-test was used for inter-group Comparison. p-value of <0.05 is considered as statistically significant. SPSS (Statistical Software for Social Sciences) version 20 was used.

Results: The whole blood transfusion in the two groups was non-significant both intra-operative and post-operative period. While a comparison of FFP transfusion during an intra-operative period in Sonoclot group was significant. Platelets were administered in the post-operative period and comparison in the two groups was not significant. A comparison of 24 hr drain output in two groups of patients was non-significant.
Conclusions: It allows the diagnosis of an exact cause of hemostatic abnormality i.e. deficiency of coagulation factors or fibrinogen or platelet function.