Abstract Craniopharyngiomas are histologically benign neuroepithelial tumors of the CNS that are predominately observed in children aged 510 years. People may present with bitemporal inferior quadrantanopia leading to bitemporal hemianopsia, as the tumor may compress the optic chiasm These tumors arise from squamous cell embryologic rests found along the path of the primitive adenohypophysis and craniopharyngeal duct. Although histologically benign, these tumors frequently recur after treatment. In addition, because they originate near critical intracranial structures (eg, visual pathways, pituitary gland, hypothalamus), both the tumor and complications of curative therapy can cause significant morbidity. These characteristics have led to various treatment approaches, and disagreement continues regarding optimal treatment in children with this disease. Other names are Rathke pouch tumors, hypophyseal duct tumors, or adamantinomas. Evidence suggests that adult craniopharyngiomas are histologically and biologically different from paediatric craniopharyngiomas; however, only childhood craniopharyngiomas are discussed in this article.
Keywords: Craniopharyngiomas; Benign; Quadrantanopia; Bitemporal Hemianopsia; Neuroepithelial Tumors; Primitive Adenohypophysis and Craniopharyngeal Duct.