Introduction: The femoral artery is the continuation of external iliac artery and it enters the femoral triangle behind the inguinal ligament at mid-inguinal point (mid-Point between the anterior superior iliac spine and pubic symphysis). The profunda femoris artery usually arises from the lateral aspect of the femoral artery. The anatomical knowledge of the profunda femoris artery is very important to prevent inadvertent damage to it during clinical procedures.
Aim and Objectives: Aim of the present study was to discuss the variations in origin of the profunda femoris artery and their clinical significance.
Materials and Methods: The study was conducted on 40 lower limbs in 20 embalmed human cadavers of unknown age, from the Department of Anatomy of Al–Falah School of Medical Science and Research Center, Dhauj, Faridabad.
Results: The most common site of origin of PFA is lateral aspect of FA. In the present study done on 40 lower limbs we found lateral, posterolateral, posterior and medial origins of profunda femoris artery. The most common range of the distance of origin of PFA from midinguinal point was 21 - 30 mm.
Conclusion: This study will be very helpful to the surgeons, radiologist and plastic surgeons to understand possible variations in Profunda femoris artery while performing procedures on FA.