Introduction: Waste is generated as consequences of household activities such as the cleaning, cooking, repairing empty containers, packaging, huge use of plastic carry bags. Many times these waste gets mixed with biomedical waste from hospitals and clinics. The improper management and lack of disposal technique of the domestic waste pollutes to the environment. Aims and objectives: To assess the level of knowledge and practice of household waste management among rural women, and to identify the association between level of knowledge with selected socio demographic variables of rural women. Materials and methods: Cross sectional descriptive study was conducted among women (210) residing in the village Ramanathapuram, Pondicherry in the age group of 18–55 years. Results: The knowledge level of the rural women regarding disposal of waste was inadequate as mean score was less than 50% of the total score (13). The practice of waste disposal was inappropriate. Conclusion: The study concluded that the most of the women residing in the rural area were having inadequate knowledge, practice was inappropriate at most of the situation.