Background and objectives: Many different techniques are currently used to join segments of the gastrointestinal tract following resection. This study is intended to study the feasibility of single layer technique in our setup, to study the disease groups undergoing gastrointestinal resection and anastomoses, and to study safety and efficacy of polyglactin in single layer gastrointestinal anastomoses in terms of early postoperative leak. Methods: A total of 50 patients were selected randomly to represent different disease groups from 312 gastrointestinal anastomoses performed Govt Mohan Kumaramangala Medical College Hospita (GMKMCH) l, Salem, Tamilnadu during October 2012 to September 2017. Patient underwent laparotomy, resection and end to end anastomoses of gastrointestinal tract at various levels with single layer technique using polyglactin as suture material. Results: In upper GI tract most common disease in our study requiring resection and anastomoses was Meckels diverticulum 9 (18%) and lower GI tract was Intussusception 14 (28%). Out of 50 resection and anastomoses there were 2 anastomotic leaks, 1 anstomotic stricture, and 2 deaths (not related to anastomoses). Interpretation and Conclusion: Anastomoses performed in elective surgeries healed well with less complications as compared to emergency surgeries. Single layer anastomoses with vicryl is the method of choice throughout the gastrointestinal tract for various diseases with less complications in pediatric age also.

Keywords: Single Layer; Anastomoses; Disease Groups; Gastrointestinal; Anastomotic Leak; Complication.