Du perforation is common complication of PUD. Patients needs prompt resuscitation and surgical suturing of perforation. Mortality rate [1] is 15.2% and morbidity [1] is 5.2%. But mortality is low in early diagnosis & prompt treatment. Again operative outcome depends on skill, experience and procedure. Materials: This is retrospective study in Jorhat Medical College & Hospital where total 75 numbers of patients from January 2010 to December 2017 were analysed to evaluate effective and save open surgical suture. Result: In one layer repair two patients had bile leak and both expired. 3 patients had symptoms of APD. In one layer suture two patients had bile leak and both died. Definitive surgery is always restricted to its complication. In follow up, three patients were assessed to have clinical feature of APD. It responded to PPI. Laparoscopic repair has no provent advantage in PPU. Mean Age is 39.61 in Group A and 36.37 in Group B. Standard Deviation is ± 3.09 in Group A and ± 5.86 in group B. Chi-Square Test is 4.022 and P-value is 0.0525. So P value is just significant at 5% or not significant. Gender is not related to age for diseases as P-value is high. Conclusion: Two layer open surgical suture in PPD is found safe and secured than one layer suture.