Abstract Introduction: Giant cell tumor of the tendon sheath (GCTTS) is a solitary benign soft- tissue tumor. It is the second most common tumor of the hand. GCTTS is most commonly found in the distal interphalangeal (DIP) joint of hand and very common in 4th decade of life. Our diligent search through available literature could not find any consensus on the etiology, prognostic factors and treatment modalities of GCTTS. We did prospective study of twenty patients with GCTTS of hand who underwent complete excision of the tumour, which was first of such kind of study. Methods: A prospective non-randomized study of twenty patients with GCTTS of hand, who underwent excision of the tumor was done. ompilation of the parameters were done which included, age and gender of patient, presentation of tumor, tumor size and location. Pre-operative X-ray of hand and wrist, ultrasonography and/or MRI whenever required was done. FNAC findings and post operative histopathological reports were recorded carefully. All the patients were followed up at months 3 and 6 and year 1 post-operatively, and recurrence rate was carefully noted. Results: In our study of 20 patients, 13 were female and 7 were female. The mean age of patients was 44 years. Patients presented, an average 14 months after initial onset of symptoms. Size of tumor on clinical examination was mean diameter of 3.4 cm in its greatest dimension. Most common location of the tumor was the palmar aspect of the hand on the thumb followed by little finger. Four patients had neurovascular bundle involvement who presented with predominant pain and swelling. All patients underwent surgical excision without adjuvant radiotherapy. No surgical complications were noted in any of the cases.In follow up study up to the 1 year, 2 patients had recurrence.
Keywords: Wrist Thumb Radiotherapy; Adjuvant Giant Cell Tumors Fingers Tendons.